Bradley Cooper's ex-wife is weighing in on the chemistry between he and Lady Gaga at the Oscars.

Following their intimate performance at the 91st Annual Academy Awards, many celebrities and viewers were left wondering about the status of the A Star is Born co-star's relationship. David Spade posted a snapshot from the duet on Instagram, questioning, "Is there any chance these two aren't f---ing?" Cooper's ex-wife Jennifer Esposito shared her thoughts, according to a report from Entertainment Tonight.

"Ha," she wrote.

Esposito and Cooper were married for less than a year from 2006 to 2007. She has not said any more about the relationship between her former beau and Gaga, 32. Neither star responded to her comment or Spade's post.

Gaga posted about Cooper, 44, on Twitter after the pair took the stage together. She showed her appreciation for the actor, who played Jackson Maine in A Star is Born.

"Nothing could be more special than sharing this moment at the Oscars with a true friend and artistic genius," she wrote alongside a picture of them sitting side-by-side at the piano.

Rumors have been swirling about Gaga and Cooper's relationship since long before they took the stage together. Speculation intensified after Gaga ended her engagement to Christian Carino. Still, Cooper is in a relationship with Irina Shayk and has been for some time. The pair share a child together.